Carotid Disease and Management.

Carotid artery stenosis is a leading cause of stroke, and 25% of patients experience a recurrent stroke within 5 years. Early detection and treatment are important to reduce the risk of stroke. Optimal medical therapy should be ensured among these patients regardless of symptom status.

Experimental myositis: an optimised version of C-protein-induced myositis.

Introduction: Inflammatory myopathies (IM) are a group of severe autoimmune diseases, sharing some similarities, whose cause is unknown and treatment is empirical.While C-protein-induced myositis (CIM), the most currently used mouse model of IM, has removed some roadblocks to understand and improve the treatment of IM, it has only been partially characterised and its generation limited by poor reproducibility. This study aimed at optimising the generation and the characterisation of CIM.

[New insights of vitamin D-based therapy for prostate cancer].

Prostate cancer is the third leading cause of cancer-related death among men in developed countries. Hormone and chemotherapy are the standard of care for advanced prostate cancer, but most patients develop resistance. Therefore, new therapeutic strategies are needed to improve the clinical management of prostate cancer.