Genetic and Clinical Predictors of Hearing Loss Among Patients with CHARGE Syndrome.

CHARGE syndrome (CS) is a genetic disorder caused by pathogenic variants within chromodomainhelicase DNA-binding protein 7 (CHD7). The classical presentation includes coloboma,congenital heart defects, atresia of the choanae, retardation of development, genital hypoplasia, andear anomalies. Clinical presentation varies widely by type and severity.

Meeting Challenges in the Diagnosis and Treatment of Glaucoma.

Glaucoma, a progressive and multifactorial optic neurodegenerative disease, still poses significant challenges in both diagnosis and management and remains a perpetual enigma [...

Complications of Cholesteatoma.

Complications of cholesteatoma result from characteristic inflammatory and resorptive processes that erode the structures of the middle and inner ear with potential to spread locally. Common intratemporal complications include hearing loss, facial nerve palsy, labyrinthine fistula, and dysgeusia. Extratemporal complications, though less common, may be life-threatening, and include cerebrospinal fluid leak and encephalocele, meningitis, epidural and intraparenchymal abscesses, subdural empyema, and otic hydrocephalus.

Management of Pediatric Tracheocutaneous Fistulae.

Pediatric tracheocutaneous fistulae are best managed initially with secondary closure techniques. This procedure can be performed twice before significant further evaluation should be undertaken. Further studies are still needed with larger patient volumes to power management minutiae for pediatric tracheocutaneous fistulae.

Serous Choroidal Detachment Associated with Suspected Contralateral Cavernous Sinus Thrombosis.

Purpose: To describe a case of choroidal detachment (CD) secondary to cavernous sinus thrombosis (CST).

Methods: Case report.

Results: A 73-year-old male with a history of primary open angle glaucoma and pseudophakia presented with retrobulbar pain, blurred vision, and diplopia of the right eye.