Publications by authors named "D Chiba"

Article Synopsis
  • * Taurine (TAU), an essential amino acid with protective properties against tissue toxicity from chemotherapy, was hypothesized to mitigate the adverse effects of 5-FU, particularly in relation to colorectal cancer.
  • * In a study with rats, combinations of taurine and 5-FU showed promising results, reducing adenocarcinoma occurrence compared to 5-FU alone, suggesting that taurine may enhance the effectiveness of 5-FU
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Introduction: Furoxan and benzofuroxan are compounds containing an N-oxide function, known for their diverse pharmacological properties, including antimicrobial and antiinflammatory effects. This study aimed to investigate these activities using an in-house library of N-oxide compounds.

Method: Twenty compounds were tested against both Gram-positive and Gram-negative bacteria, including Cutibacterium acnes (C.

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Background: Anterolateral knee laxity (ALLx) has been linked to tears of the lateral meniscus (LM) and anterior cruciate ligament (ACL) injury.

Purpose: To investigate the longitudinal relationship between the signal intensity (SI) of the repaired LM on magnetic resonance imaging (MRI) and residual ALLx after ACL reconstruction (ACLR).

Study Design: Cohort study; Level of evidence, 3.

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Background: Bone marrow lesion (BML) is an important magnetic resonance finding (MRI) finding that predicts knee osteoarthritis. The purpose of this study was to investigate the influence of proximal tibial morphology on BML, including the spreading root sign (SRS), in women without radiographic knee osteoarthritis (OA). It was hypothesized that varus alignment and a greater posterior tibial slopes (PTS) are associated with BML.

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Article Synopsis
  • The study focuses on creating a new phantom to enhance the evaluation of clinical Chemical Exchange Saturation Transfer (CEST) imaging, addressing issues like field inhomogeneities and contrast differences.
  • The phantom consists of two sections: one for analyzing local frequency offsets and another for assessing the CEST effect using varying concentrations of egg white albumin.
  • Results from the 3 Tesla MR scanner showed that B field corrections affected the Z-spectrums, with higher B amplitudes leading to broader curves and significantly increased MTR values for the albumin samples.
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