Insulin-pump use in everyday practice: data from an exhaustive regional registry in France.

Aim: The aim of this study is to evaluate the effectiveness and safety of continuous subcutaneous insulin infusion (CSII) under real-life conditions among all patients treated with CSII in the south of Paris.

Methods: The 42 diabetologists practising in the region enrolled all patients treated with CSII or admitted for CSII initiation. During the study visit, the data for pump use and clinical results were recorded.

[Cerebral magnetic resonance imaging in iatrogenic Creutzfeldt-Jacob disease].

Introduction: We describe here the cerebral cerebral magnetic resonance (MRI) abnormalities observed in a case of iatrogenic Creutzfeldt-Jacob disease (CD).

Case: A 37 year-old man had been treated for pituitary dwarfism during adolescence with contaminated growth hormone. Neurological symptoms nearly two decades later suggested CJD.

[A large para-renal PEComa].

We report the case of a 45-year-old man with a voluminous para-renal mass. The tumor was composed of epithelioid or spindle-shaped eosinophilic and clear cells with some atypia and an elevated mitotic count. The immunohistochemical study was positive for anti-HMB45 antibodies and anti-actin-antibodies and negative for epithelial markers and PS100 antibodies.

Primary chronic interstitial nephritis in Crohn's disease.

Background & Aims: In Crohn's disease, cases of interstitial nephritis with renal failure have been reported in connection with the use of mesalamine.

Methods: We observed 4 patients with severe interstitial nephritis proven by examination of kidney biopsy specimens. Renal failure was discovered before or simultaneously with the diagnosis of Crohn's disease, and patients were not treated with mesalamine.

[Chemotaxis and collagen].

The authors evaluate the chemotactic properties of collagen and collagen derived fragments, according to literature datas. In experimental conditions, collagen can be chemotactic for human blood monocytes, fibroblasts and various malignant cells but not polymorphonuclear. The meaning of these facts and their possible role in the genesis of osteo-articular diseases are also discussed.