Publications by authors named "D Chapman-Jones"

Background: Multi-resistant Gram-negative bacteria (GNB) survive in hospital drains in traps that contain water and may ascend into the sink because of splashes, or biofilm growth.

Aim: To investigate whether the 'Tuba Drain' (TD) a long, bent, continually descending copper tube between the sink outlet and the trap prevents the ascent of bacteria.

Methods: After initial laboratory tests confirmed that the TD prevented bacteria in the U-bend from splashing upwards into the sink outlet, TDs were assessed in a randomized, blinded trial in a hospital outpatient department built in 2019.

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This paper is written in response to a publication in the in 2018 by Guest et al., 'Cost-effectiveness of an electroceutical device in treating non-healing venous leg ulcers: results of an RCT'. The publication and subsequent analysis of the paper provides a vehicle for a wider debate about the care of people with wounds, including who manages the wound, how resources are allocated and the use of supplemental technologies.

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Article Synopsis
  • The study aimed to understand how targeted electrical stimulation (ES) affects gene expression in healthy skin, as previous research suggested it can enhance wound healing.* -
  • Researchers used a noninvasive ES device on healthy volunteers for 48 hours and found changes in the expression of 105 genes, most of which were down-regulated.* -
  • The findings indicate some genes modified by ES are similar to those activated in actual skin wounds, opening up new research opportunities for improving healing in patients with chronic wounds.*
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