Publications by authors named "D Chaparro"
Article Synopsis
- Chronic kidney disease (CKD) and cardiovascular disease (CVD) co-occur, showing distinct differences in how they affect males and females, despite similar risk factors for both sexes.
- In a study using male and female mice, males on a high-adenine diet developed more severe CKD and displayed significant cardiac issues, like left ventricular hypertrophy and prolonged QTc intervals, compared to females.
- A new ECG marker called S-J duration was identified, increasing with disease progression, and highlighting the importance of studying these sex-specific cardiac differences in CKD-induced CVD.
Elastic fibers are crucial for aortic valve (AoV) function and are generated and maintained by valvular interstitial cells (VICs). VICs exhibit diverse phenotypes, yet the specific subpopulation responsible for producing and regulating elastic fibers remains unclear. This gap in knowledge is significant, given that elastin (Eln) abnormalities lead to congenital AoV defects and initiate AoV diseases.
View Article and Find Full Text PDFReactive molecular dynamics is used to investigate the oxidation of anisotropic silver nanoparticles (nano-Ag) of various shapes, including sphere, cube, disk, cylinder, triangle, and pyramid. The effect of the nano-Ag initial morphology on their stability and composition during oxidation is quantified. Surface oxidation at 600 K leads to the formation of a core-shell structure for all nano-Ag shapes.
View Article and Find Full Text PDFMangroves are impacted by multiple environmental stressors, including sea level rise, erosion, and plastic pollution. Thus, mangrove soil may be an excellent source of as yet unknown plastic-transforming microorganisms. Here, we assess the impact of polyethylene terephthalate (PET) particles and seawater intrusion on the mangrove soil microbiome and report an enrichment culture experiment to artificially select PET-transforming microbial consortia.
View Article and Find Full Text PDFIntroduction: Reports regarding the correlation and effect size of change of the full spectrum of quality of life and disease severity measures applied in-person to patients with atopic dermatitis are scarce.
Objectives: To assess quality-of-life with 3 different instruments and to evaluate disease severity indices and to determine their correlation and effect size of change between two measurements.
Materials And Methods: Patient-level data were obtained through two in-person visits.