Publications by authors named "D Castelino"
Article Synopsis
- Excessive fluoride exposure can cause oxidative stress and damage metabolic organs, leading to toxicity in the liver and kidneys.
- A study was conducted on Wistar rats divided into four groups, with some receiving sodium fluoride alone and others receiving fluoride with different doses of betanin from beetroot for 90 days.
- Results showed that betanin treatment reduced markers of liver and kidney damage and improved oxidative stress indicators, suggesting it could potentially protect against fluoride-induced organ toxicity.
The synthesis and study of a series of pseudohalides of boron subphthalocyanine (BsubPc) are reported. Each pseudohalide has been compared to the more common chloride and bromide of BsubPc, and we have found that most react slower under standard phenoxylation and hydrolysis conditions. Three pseudohalides (TsO-BsubPc, MsO-BsubPc, and BsO-BsubPc) do not hydrolyze at all even after prolonged periods of time in the presence of water.
View Article and Find Full Text PDFBackground: Lymphocytopenia is a common finding in hospital patients especially since the advent of automated differential leukocyte counters. The causes and significance of lymphocytopenia are generally poorly understood. There has been no large-scale study of its significance for 25 years.
View Article and Find Full Text PDFThe regulation of blood coagulation is dependent on a complex interplay between procoagulant, anticoagulant and fibrinolytic proteins. Most of these proteins are synthesised in the liver and their levels are altered in patients with liver disease. The liver also plays an important role in the regulation of haemostasis throughout the clearance of activated clotting factors.
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