Publications by authors named "D Castagnola"

Background: Group A Streptococcus, once the most common causes of puerperal sepsis, is now a rare cause of postpartum fever.

Case: A term 27-year-old woman presented after spontaneous membrane rupture. After an uncomplicated vaginal delivery, she became febrile without a source of infection.

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Cutaneous endometriosis is an infrequent pathology whose etiopathogenesis is still uncertain. A case of cutaneous endometriosis at the surgical scar level following cesarean section is reported. Moreover, the aspects which might facilitate the diagnostic approach and a correct therapeutic management are underlined.

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Article Synopsis
  • The text presents a rare case study of angiomyofibroblastoma (AMF) and aggressive angiomyxoma (AAM) in female genital tissues, examining their histogenesis and biological behavior through immunohistological evaluation.
  • Findings indicate that AAM has a unique composition of glycosaminoglycans and expresses certain proteins, like vimentin and CD44, which may contribute to its aggressive nature, while AMF shows a different protein expression profile.
  • Both tumors likely originate from a common myofibroblastic progenitor from the lower female genital tract, with AAM exhibiting a potential for greater neoplastic transformation due to its unique characteristics.
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Nineteen patients with simple endometrial hyperplasia presenting metrorrhagia or menometrorrhagia were treated with 4 injections of Goserelin depot, one every 4 weeks. 12/19 patients were refractory after previous medical therapy. The treatment with Goserelin depot resulted in a complete remission of the symptoms, occurring within the first month of treatment and still present after a median follow-up of 12 months, and in the normalization of the histological profile.

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Spinal lipomas account for 5% of the tumors of the spinal cord, frequently present already at birth. Most commonly they are associated with forms of dysraphism, but lipomas without bony involvement are considered dysembriogenetic lesions too. Children with lipoma frequently have intact neurological functions, but may become symptomatic later on.

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