Publications by authors named "D Casabonne"
Lifetime exposure to brominated trihalomethanes in drinking water and swimming pool attendance are associated with chronic lymphocytic leukemia: a Multicase-Control Study in Spain (MCC-Spain).
Carolina Donat-Vargas Manolis Kogevinas Yolanda Benavente Laura Costas Elias Campo Delphine Casabonne
J Expo Sci Environ Epidemiol
January 2024
Article Synopsis
- - This study investigates the potential link between chronic lymphocytic leukemia (CLL) and exposure to trihalomethanes (THMs) and nitrate in drinking water, along with swimming pool attendance.
- - Researchers collected data from CLL patients and control subjects in Spain, analyzing water quality and pool usage, ultimately finding that long-term exposure to THMs and frequent pool use were associated with higher odds of developing CLL.
- - The findings suggest that even low levels of THMs in drinking water and regular swimming pool attendance may contribute to CLL risk, highlighting the need for further research into these environmental factors.
Article Synopsis
- The study investigated the link between artificial sweeteners (AS) like aspartame and certain cancers, using a population sample from the MCC-Spain study, which included various cancer cases and controls.
- Overall, the research found no significant association between AS consumption and cancer risk; however, some links were observed specifically for participants with diabetes.
- High consumption of aspartame was correlated with an increased risk of stomach cancer, while a lower risk was noted for breast cancer in the same group, highlighting the need for cautious interpretation due to small sample sizes for certain cancers.
Article Synopsis
- * A study investigated whether 41 of these genetic variants could predict overall survival (OS) and time to first treatment (TTFT) in 1,039 CLL patients but found only weak associations that lacked significance after adjusting for multiple tests.
- * The findings indicated that genetic risk variants do not significantly affect survival or disease progression in CLL patients, with polygenic risk scores providing only modest predictive ability for patient outcomes.