The ratio of reactive oxygen and nitrogen species determines the type of cell death that bacteria undergo.

Reactive oxygen and nitrogen species (RONS) are emerging as a novel antibacterial strategy to combat the alarming increase in antimicrobial resistance (AMR). RONS can inhibit bacterial growth through reactions with cellular molecules, compromising vital biological functions and leading to cell death. While their mechanisms of action have been studied, many remain unclear, especially in biologically relevant environments.

Wound Healing Promotion via Release of Therapeutic Metallic Ions from Phosphate Glass Fibers: An and Study.

Biomaterials capable of promoting wound healing and preventing infections remain in great demand to address the global unmet need for the treatment of chronic wounds. Phosphate-based glasses (PG) have shown potential as bioresorbable materials capable of inducing tissue regeneration, while being replaced by regenerated tissue and releasing therapeutic species. In this work, phosphate-glass-based fibers (PGF) in the system PO-CaO-NaO added with 1, 2, 4, 6, and 10 mol % of the therapeutic metallic ions (TMI) Ag, Zn, and Fe were manufactured via electrospinning of coacervate gels.

Use of Virtual Reality in Patients with Acquired Brain Injury: A Systematic Review.

Background And Objectives: ABI is found in all societies as the most severe, disabling neurological disorder. A cognitive rehabilitation program is essential for the clinical recovery of these patients, improving functional outcomes and quality of life. Modern technologies such as virtual reality (VR) offer several advantages over traditional therapies, including the ability to engage people in simulated performance of functional tasks.

Highly porous phosphate-based glasses for controlled delivery of antibacterial Cu ions prepared sol-gel chemistry.

Mesoporous glasses are a promising class of bioresorbable biomaterials characterized by high surface area and extended porosity in the range of 2 to 50 nm. These peculiar properties make them ideal materials for the controlled release of therapeutic ions and molecules. Whilst mesoporous silicate-based glasses (MSG) have been widely investigated, much less work has been done on mesoporous phosphate-based glasses (MPG).