Treatment of primary tumor in metastatic head and neck Carcinoma: A systematic review and Meta-Analysis.

Introduction: The treatment of primary tumors in metastatic squamous cell carcinoma of the head and neck (HNSCC) is a complex and debated issue. This study evaluates the impact of treating primary tumors on overall survival (OS) and progression-free survival (PFS) in metastatic HNSCC through a systematic review and meta-analysis, with a focus on identifying potential biases and limitations in the available evidence.

Materials And Methods: A comprehensive literature search was conducted in PubMed, EMBASE, and The Cochrane Library for studies published up to January 2024.

Human papillomavirus infection and non-oropharyngeal head and neck cancers: an umbrella review of meta-analysis.

Objective: The causative and prognostic roles of human papillomavirus (HPV) in non-oropharyngeal squamous cell carcinoma of the head and neck are uncertain. This umbrella review assessed the strength and quality of evidence and graded the evidence derived from published meta-analyses on this subject.

Data Sources: MEDLINE, Embase, and the Cochrane Library were searched.

Comparison of different treatments for HPV+ oropharyngeal carcinoma: a network meta-analysis.

Introduction: Treatment of human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) is rapidly evolving. Despite either surgery or radiotherapy (RT), with or without chemotherapy (CT), being acceptable in intermediate and locally advanced diseases, there is uncertainty regarding the best treatment option for these patients. Therefore, we performed a network meta-analysis (NMA) to compare the relative efficacy of different treatments for HPV+ oropharyngeal carcinoma.

New low-cost magnifying device for temporal bone laboratory.

Temporal bone dissection has important role in educating and training oto and skull base surgeons. Mounting of a temporal bone laboratory is expensive. A dedicated magnifying system, such as a surgical microscope or an endoscopic equipment, represents one of the most significant costs.

A novel integrated platform for the identification of surgical margins in oral squamous cell carcinoma: results from a prospective single-institution series.

Background: The optimal surgical margins assessment is capital in oral squamous cell carcinoma (OSCC) management. We evaluated the clinical benefits of integrating intraoperative macroscopic margin (MM) assessment and narrow band imaging (NBI).

Methods: Sixteen OSCC patients eligible for surgery were prospectively enrolled.