Publications by authors named "D Campisi"
Article Synopsis
- Autophagy is a crucial process in cells that helps break down and recycle damaged or unnecessary components to maintain balance and health within the cell.
- It can occur in two ways: selective, where specific materials are targeted, and nonselective, where a broader range of cellular material is engulfed during stress or starvation.
- The research continues to explore how these processes work, particularly the formation of structures called omegasomes and phagophores in nonselective autophagy in mammals.
The hallmark of non-selective autophagy is the formation of cup-shaped phagophores that capture bulk cytoplasm. The process is accompanied by the conjugation of LC3B to phagophores by an E3 ligase complex comprising ATG12-ATG5 and ATG16L1. Here we combined two complementary reconstitution approaches to reveal the function of LC3B and its ligase complex during phagophore expansion.
View Article and Find Full Text PDFVaccination against SARS-CoV-2 has been demonstrated to be safe during gestation. Nevertheless, there are no robust data investigating the entity of maternal antibodies' transmission through the placenta to the newborn and the persistence of the antibodies in babies' serum. The objective of this study is to assess the maternal antibody transmission and kinetics among newborns in the first months of life.
View Article and Find Full Text PDFBackground: Acute coronary syndromes (ACS) are a major cause of morbidity and mortality. As cytomegalovirus (CMV) may contribute to cardio-vascular (CV) manifestations, we sought to provide a proof-of-concept for the involvement of coronary and/or systemic CMV-reactivation as a possible ACS trigger.
Methods: We prospectively enrolled consecutive patients undergoing a coronary angiography for ACS (acute-cases, N.
The emergence of conductive 2D and less commonly 3D coordination polymers (CPs) and metal-organic frameworks (MOFs) promises novel applications in many fields. However, the synthetic parameters for these electronically complex materials are not thoroughly understood. Here we report a new 3D semiconducting CP Fe (C O ) , which is a fusion of 2D Fe-semiquinoid materials and 3D cubic Fe (C O ) materials, by using a different initial redox-state of the C O linker.
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