Publications by authors named "D Cadar"

Dengue is an increasing threat to individuals living in or visiting endemic countries. Effective vaccines have become available, but their use in travelers is typically only recommended to individuals with documented prior infection. We present a fatal case of severe dengue in an unvaccinated traveler without known prior dengue virus infection but longitudinal serologic and molecular evidence for secondary infection.

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  • Crimean-Congo hemorrhagic fever virus (CCHFV) is a serious tick-borne virus that can lead to severe illness and has a high death rate.
  • The report details the genomic analysis of a CCHFV strain linked to North Macedonia's first outbreak in over 50 years.
  • It highlights the critical role of genomic surveillance in monitoring how the virus evolves and spreads in this area.
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  • Research investigates the link between socioeconomic position (SEP) and the transition between cognitive states, including neurocognitive impairment and mortality risk.
  • The study found significant differences in cognitive state transitions based on SEP, revealing that higher wealth is associated with a greater likelihood of improving cognitive function.
  • Additionally, lower education levels correlate with increased mortality risk following dementia onset, suggesting that socioeconomic factors may influence both cognitive health and longevity.
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Arboviral diseases are a growing global health concern. Pre-existing autoantibodies (auto-Abs) neutralizing type I interferons (IFNs) can underlie encephalitis due to West Nile virus (WNV) (∼40% of patients) and tick-borne encephalitis (TBE, due to TBE virus [TBEV]) (∼10%). We report here that these auto-Abs can also underlie severe forms of rarer arboviral infections.

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Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Crocidura leucodon). The known BoDV-1-endemic area is remarkably restricted to parts of Germany, Austria, Switzerland and Liechtenstein. To gain comprehensive data on its occurrence, we analysed diagnostic material from suspected BoDV-1-induced encephalitis cases based on clinical and/or histopathological diagnosis.

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