Publications by authors named "D CORTI"

Article Synopsis
  • There are three potential future paths for SARS-CoV-2: ongoing severity, an influenza-like severity, or a transition to a milder endemic disease.
  • A study utilized data from various health sources to compare SARS-CoV-2 infections with influenza regarding hospitalization and viral impact, assessing over 424,000 cases.
  • The results suggest that SARS-CoV-2 shows lower hospitalization rates compared to influenza and responds better to antiviral treatments, indicating a trend towards a less severe endemic state for the virus.
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Article Synopsis
  • * The study utilizes a generative AI model called Orion to analyze blood samples from 1,050 individuals with non-small cell lung cancer (NSCLC) and matched controls, focusing on orphan non-coding RNAs.
  • * Orion significantly outperforms traditional methods, achieving 94% sensitivity and 87% specificity in cancer detection, and shows over 30% higher sensitivity on validation datasets compared to other approaches.
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The atomic force microscope (AFM), as it is able to characterize surface topography as well determine the AFM cantilever tip-surface force, proves effective at estimating the value of the Hamaker constant, , for a given solid material. Two main AFM-based methods have been proposed for estimating values of . In the approach-to-contact (AtC) method, Hamaker constants are inferred from the deflections at which the AFM tip first jumps into contact with the substrate.

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Porcine delta-coronavirus (PDCoV) spillovers were recently detected in febrile children, underscoring the recurrent zoonoses of divergent CoVs. To date, no vaccines or specific therapeutics are approved for use in humans against PDCoV. To prepare for possible future PDCoV epidemics, we isolated PDCoV spike (S)-directed monoclonal antibodies (mAbs) from humanized mice and found that two, designated PD33 and PD41, broadly neutralized a panel of PDCoV variants.

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