Publications by authors named "D CARROLL"

Indigenous wellness has been defined in varying contexts by diverse Indigenous Peoples. The existing indicators used to measure wellness are often defined from a Western perspective. Despite the rich conceptualizations of Indigenous wellness, there exists a notable gap in how it can be measured in contemporary contexts through an Indigenous lens.

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Objectives: Patients are often discharged to a skilled nursing facility (SNF) for postacute rehabilitation. Functional outcomes achieved in SNFs are variable, and costs are high. Especially for accountable care organizations (ACOs), home-based postacute rehabilitation offers a high-value option if outcomes are not compromised.

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Background: Lasofoxifene, a novel endocrine therapy (ET), showed antitumor activity versus fulvestrant in women with ESR1-mutated, metastatic breast cancer (mBC) that progressed on prior ET (phase 2, ELAINE 1 study). We investigated changes in genitourinary syndrome of menopause (GSM) vulvar-vaginal symptoms with lasofoxifene and how patient/disease characteristics affect baseline vulvar-vaginal symptoms in ELAINE 1.

Methods: Women were randomized to oral lasofoxifene 5 mg/day or IM fulvestrant 500 mg (days 1, 15, and 29, then every 28 days) until disease progression/severe toxicity.

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Article Synopsis
  • The discharge of calved ice and subglacial runoff in Disko Bay, home to Sermeq Kujalleq glacier, is expected to influence marine biogeochemistry, particularly affecting the marine silica cycle due to elevated dissolved silica (dSi) from glaciers.
  • The study analyzes silica dynamics in various regions around Disko Bay, finding that land-terminating glaciers show conservative dSi patterns, whereas marine-terminating glaciers significantly alter nutrient distribution through subglacial discharge plumes.
  • The research quantifies contributions to dSi enrichment, highlighting that a large fraction comes from saline water entrainment, with minor contributions from icebergs and amorphous silica dissolution, ultimately adding a small but significant dSi flux to the environment.
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Background: The American Association of Colleges of Pharmacy Curriculum Outcomes and Entrustable Professional Activities (COEPA) recognize the need for social determinants of health (SDH) education for pharmacy learners. However, there is a dearth of published strategies for incorporating comprehensive SDH education in Doctor of Pharmacy curricula. The objectives of this study were to: 1) highlight unpublished exemplars of SDH teaching models and 2) propose strategies for teaching SDH.

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