Publications by authors named "D C dela Paz"

Objective: This study was conducted to evaluate the time gap between earliest head CT with a significant Radscale score and ventriculo-peritoneal (VP) shunt placement.

Material And Methods: The study is a retrospective observational analytic study. The study population includes idiopathic normal pressure hydrocephalus (iNPH) patients treated with a VP shunt in a single center between the years 2016 and 2022 and have at least 2 CTs, one in proximity to diagnosis and another obtained at an earlier time point.

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  • * Results showed a significant drop in the CAR on the third day, with recovery observed on the fourth day, and specific cytokines (like IL-6 and CXCL1) were found to correlate with these cortisol patterns.
  • * The findings suggest that the CAR may reflect psychological burnout and highlight how stress affects immune function, offering insights for managing stress in high-pressure professions like military and medical fields.
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Mutation of the GABRA1 gene is associated with neurodevelopmental defects and epilepsy. GABRA1 encodes for the α1 subunit of the γ-aminobutyric acid type A receptor (GABAR), which regulates the fast inhibitory impulses of the nervous system. Multiple model systems have been developed to understand the function of GABRA1, but these models have produced complex and, at times, incongruent data.

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  • * The study uses the Integrated Source Apportionment Method in the Community Multiscale Air Quality model to analyze the causes of summertime ozone levels in Madrid, revealing that about 70% of these levels come from non-local sources.
  • * Local emission sources, particularly road traffic, significantly contribute to ozone peaks, and the effectiveness of local measures is enhanced during unfavorable weather conditions, indicating that this modeling approach can guide future pollution control strategies.
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A 51-year-old male with a history of Cacchi-Ricci disease and long-standing infection with various species of presented with recurrent symptoms of right-sided flank pain. Numerous renal calculi were identified on imaging. The etiology of the calculi had not been previously elucidated.

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