Objective: This study was conducted to evaluate the time gap between earliest head CT with a significant Radscale score and ventriculo-peritoneal (VP) shunt placement.
Material And Methods: The study is a retrospective observational analytic study. The study population includes idiopathic normal pressure hydrocephalus (iNPH) patients treated with a VP shunt in a single center between the years 2016 and 2022 and have at least 2 CTs, one in proximity to diagnosis and another obtained at an earlier time point.
Mutation of the GABRA1 gene is associated with neurodevelopmental defects and epilepsy. GABRA1 encodes for the α1 subunit of the γ-aminobutyric acid type A receptor (GABAR), which regulates the fast inhibitory impulses of the nervous system. Multiple model systems have been developed to understand the function of GABRA1, but these models have produced complex and, at times, incongruent data.
View Article and Find Full Text PDFA 51-year-old male with a history of Cacchi-Ricci disease and long-standing infection with various species of presented with recurrent symptoms of right-sided flank pain. Numerous renal calculi were identified on imaging. The etiology of the calculi had not been previously elucidated.
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