Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders.

To investigate the regulatory mechanism mediated by hypothalamic OPN5 on seasonal changes in the reproductive activities of domestic geese, 60 Magang ganders in their breeding period were selected for the experiment and evenly divided into an immunization group(OPN5-IM) and a control group. On days 0, 15 and 30, ganders in the immunized group were immunized with OPN5-KLH protein vaccine, and ganders in the control were immunized with the same amount of blank emulsified vaccine. Additionally, 120 female geese were provided to stimulate the reproductive activities of male geese.

Sirt6 regulates the Notch signaling pathway and mediates autophagy and regulates podocyte damage in diabetic nephropathy.

To investigate the role of silent information regulator 6 (SIRT6) in regulating podocyte injury in diabetic nephropathy (DN) through autophagy mediated by Notch signaling pathway. A blank control group (group A), a diabetic nephropathy group (group B), and a Sirt6 intervention group (group C) were established. The group A cells were human normal glomerular podocyte cell lines (HGPCs) without any treatment.

The link between eye movements and cognitive function in mild to moderate Alzheimer's disease.

This study investigated the relationship between eye movement parameters and cognitive function in patients with mild to moderate Alzheimer's disease (AD). A total of 80 patients with AD (mild and moderate) and 34 normal controls (NC) participated. Neuropsychological assessments were conducted using the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA), while eye movements were recorded using eye-tracking technology.

Carbon reduction effect of comprehensive land consolidation and its configuration paths at the township level: A case study of Zhejiang Province, China.

Changing land use is one of the main factors influencing global climate change and the imbalance in the carbon cycle. Consequently, the focus of international organizations and the academic community is on strategies to mitigate carbon emissions or improve carbon sequestration by optimizing land use structure and function. Since 2019, China's Zhejiang Province has implemented a township-level pilot policy, exploring a comprehensive land consolidation (CLC for short) pilot policy that includes all elements of "mountains, rivers, forests, farmlands, lakes, and grasslands.

Mechanism of microplastics in the reduction of cadmium toxicity in tomato.

Soil pollution by microplastics (MPs) and cadmium (Cd) poses significant threats to agricultural production, yet their combined toxicity and underlying mechanisms remain poorly understood. Here, we examined the effects of three types of MPs-polyethylene (PE), polyvinyl chloride (PVC) and polypropylene (PP)-with particle sizes of 150 μm and 10 μm, in combination with Cd stress (5 mg/kg) on tomato (Solanum lycopersicum L.) growth.