Publications by authors named "D C Widdowson"

The Cambridge Structural Database (CSD) played a key role in the recently established crystal isometry principle (CRISP). The CRISP says that any real periodic crystal is uniquely determined as a rigid structure by the geometry of its atomic centers without atomic types. Ignoring atomic types allows us to study all periodic crystals in a common space whose continuous nature is justified by the continuity of real-valued coordinates of atoms.

View Article and Find Full Text PDF
Article Synopsis
  • Mesoporous molecular crystals are valuable for applications in separation and catalysis but are challenging to design due to competing weak interactions and a tendency for molecules to pack closely.
  • A new method combining crystal structure prediction (CSP) with structural invariants helps identify similar crystal structures of related molecules, enhancing isomorphous substitution strategies that can be unreliable.
  • This approach successfully discovered a rare low-density mesoporous hydrogen-bonded framework, which opens up opportunities for better comparison and understanding of energy-structure landscapes across different molecular crystals.
View Article and Find Full Text PDF

Objective: It is widely accepted that the early debridement of burns improves outcome. There is increasing evidence that enzymatic debridement is an effective technique for removal of full-thickness and deep-dermal burns, reducing blood loss and often the need for autologous skin grafting by avoiding over excision of the burn. We aim to highlight the potential use of this form of debridement as an alternative to surgical management in patients with electronic cigarette (e-cigarette)-associated flame burn injuries.

View Article and Find Full Text PDF

Introduction: Electronic cigarettes (EC) have been reported to be associated with burns secondary to explosions of the device or battery, or contact from overheating, resulting in flame, contact or chemical burns. In addition to this, there have also been reported cases of soft tissue and bony trauma with or without associated burns. Using collective evidence, this review aims to summarise all reported burns associated with ECs, and its implications on immediate management with a particular focus on surgical treatment.

View Article and Find Full Text PDF