Publications by authors named "D C Whiteman"
Background: Understanding the factors influencing age at melanoma diagnosis by sex and anatomic site is crucial for developing effective prevention and early detection strategies. While previous research has highlighted sex-based differences in melanoma incidence by age and anatomic distribution, the underlying mechanisms remain unclear. We aimed to investigate sex-specific patterns in melanoma age at diagnosis across different anatomic sites and thickness categories, considering the potential influence of disease progression and detection rates.
View Article and Find Full Text PDFOne in every three cancers diagnosed is a skin cancer. Europe has the global lead in the number of UV-attributable cancer cases with the highest number of melanoma cases worldwide and the second highest number of keratinocyte cancers (KC). Further increases are expected in Europe for the coming decades.
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- A study investigated the link between skin screening/surveillance and increased melanoma diagnoses using data from over 10 million Australians over several years.* -
- The results showed that individuals who were screened or surveilled had significantly higher rates of skin biopsies, excisions for suspected melanoma, and confirmed melanoma compared to those who weren't.* -
- Findings suggest that increased skin detection activities can lead to higher levels of diagnostic events and melanoma incidence, indicating a robust correlation between screening practices and skin cancer outcomes.*
Purpose: This study investigated the relationship between mucopolysaccharidosis II (MPS II) iduronate-2-sulfatase gene (IDS) variants and phenotypic characteristics, particularly cognitive impairment, using data from the Hunter Outcome Survey (HOS) registry.
Methods: HOS data for male patients (n = 650) aged ≥5 years at latest cognitive assessment with available genetic data were analyzed. Predefined genotype categories were used to classify IDS variants and report phenotypic characteristics by genotype.