Validity and Reliability of the Dutch Adaptation of the Actinic Keratosis Quality of Life Questionnaire (AKQoL).

Background: The Actinic Keratosis Quality of Life Questionnaire (AKQoL) is a disease-specific instrument to measure the impact of actinic keratosis (AK) on patients' lives.

Objective: To validate and test the psychometric properties of the AKQoL translated into the Dutch language (AKQoL-NL).

Methods: All new patients ≥50 years of age with untreated AK in a university medical center and a general hospital between August 2014 and August 2015 were eligible.

From sporadic atypical nevi to familial melanoma: risk analysis for melanoma in sporadic atypical nevus patients.

Background: Atypical nevi (AN), present in either a familial or a sporadic setting, are strong indicators of increased melanoma risk.

Objective: To estimate the extent of this risk and the extent of reclassification of sporadic to familial cases during follow-up.

Methods: We studied 167 sporadic patients with AN (>or=5).