No increase in small-solute transport in peritoneal dialysis patients treated without hypertonic glucose for fifty-four months.

Background: Glucose is widely used as an osmotic agent in peritoneal dialysis (PD), but exerts untoward effects on the peritoneum. The potential protective effect of a reduced exposure to hypertonic glucose has never been investigated.

Methods: The cohort of PD patients attending our center which tackled the challenge of a restricted use of hypertonic glucose solutions has been prospectively followed since 1992.

Registration on the renal transplantation waiting list and mortality on dialysis: an analysis of the French REIN registry using a multi-state model.

Background: Access to the renal transplantation (RT) waiting list depends on factors related to lower mortality rates and often occurs after dialysis initiation. The aim of the study was to use a flexible regression model to determine if registration on the RT waiting list is associated with mortality on dialysis, independent of the comorbidities associated with such registration.

Methods: Data from the French REIN registry on 7138 incident hemodialysis (HD) patients were analyzed.

Overestimation of the probability of death on peritoneal dialysis by the Kaplan-Meier method: advantages of a competing risks approach.

Background: In survival analysis, patients on peritoneal dialysis are confronted with three different outcomes: transfer to hemodialysis, renal transplantation, or death. The Kaplan-Meier method takes into account one event only, so whether it adequately considers these different risks is questionable. The more recent competing risks method has been shown to be more appropriate in analyzing such situations.

Paracoccus yeei: a new unusual opportunistic bacterium in ambulatory peritoneal dialysis.

Paracoccus yeei was identified as the etiologic agent of peritonitis in an ambulatory peritoneal dialysis patient. While the old biochemical identification kits are not able to identify this species, the new colorimetric VITEK 2 GN card correctly identified this isolate in 7hours. Its identity was confirmed by sequencing of the 16S rRNA gene.