Publications by authors named "D C Osmon"
Impact of pharmacist-led microbiology result follow-up post-discharge for patients undergoing inpatient infectious diseases consultation.
Antimicrob Steward Healthc Epidemiol
August 2024
Objective: The primary objective was to determine the rate of clinical actions taken post-discharge on updated microbiology results by an ID pharmacist-led team. Secondary objectives were to describe the microbiology results requiring intervention, characterize interventions by type and severity, and determine time from result to clinical review.
Design: Retrospective cohort study.
Article Synopsis
- - The study investigates demographics and treatment outcomes of patients with periprosthetic joint infections (PJIs) in the hip and knee, highlighting that these infections are often under-reported and can be confused with culture contamination.
- - A total of 35 PJIs were reviewed from January 2005 to December 2018, with findings indicating that about half were treated with chronic antibiotic suppression, while others underwent two-stage exchange arthroplasty; over two years, 94% remained free from revision.
- - The results showed that PJIs typically exhibited laboratory characteristics similar to traditional organisms, and infections cultured more rapidly than expected; both chronic antibiotic treatment and surgical options had low failure rates at mid-term follow-up.
: is an uncommon pathogen that has been reported to infect musculoskeletal structures. However, studies are largely limited to case reports, and little is known regarding management and outcomes of these infections. : We performed a multicenter retrospective cohort study of adults with culture-confirmed musculoskeletal infections at three Mayo Clinic centers in Arizona, Florida, and Minnesota from November 2011 through April 2022.
View Article and Find Full Text PDFBackground: Periprosthetic joint infection (PJI) is an uncommon, but serious complication in total joint arthroplasty. Personalized risk prediction and risk factor management may allow better preoperative assessment and improved outcomes. We evaluated different data-driven approaches to develop surgery-specific PJI prediction models using large-scale data from the electronic health records (EHRs).
View Article and Find Full Text PDFBackground: The clinical utility of rapid multiplex respiratory specimen PCR panels for pneumonia for patients with suspected pneumonia is undefined. We aimed to compare the effect of the BioFire FilmArray pneumonia panel (bioMérieux, Salt Lake City, UT, USA) with standard of care testing on antibiotic use in a real-world hospital setting.
Methods: We conducted a single-centre, open-label, pragmatic, randomised controlled trial at the Mayo Clinic, Rochester, MN, USA.