Publications by authors named "D C L Teo"

Benzylisoquinoline alkaloids (BIAs) are a class of natural compounds found in plants of the family, known for their diverse pharmacological activities. However, the extraction yields of BIAs from plants are limited, and the cost of chemical synthesis is prohibitively high. Recent advancements in systems metabolic engineering and genomics have made it feasible to use microbes as bioreactors for BIAs production.

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Purpose: Polymeric and metallic stents are commonly used to manage patients with chronic malignant ureteric obstruction (CMUO). This paper compares the outcomes of ureteral stenting via the Resonance metallic stent against its polymeric counterpart in published literature, as well as between antegrade and retrograde approaches.

Methods: A retrospective case series was conducted whereby patients who had undergone Resonance stent insertions via an antegrade route from June 2022 to May 2023 were reviewed through our electronic medical record system.

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In medical training and practice, our professional attributes, attitudes, perceptions, character traits and identities are fundamentally shaped by our lived experiences and observations in clinical and para-clinical settings instead of being inculcated through formal curriculum or classroom teaching. For instance, clinical acumen, communication skills and bedside manners are learnt through role modelling and experiential learning in the course of clinical rotations. Likewise, one's attitudes, professional behaviours and inclinations are often also influenced by direct/indirect observations of the actions of others in the medical fraternity in various clinical and non-clinical settings.

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Article Synopsis
  • A nationwide study was conducted to explore the link between COVID-19 mRNA vaccinations and autoimmune hepatitis (AIH), which had mostly been reported in isolated case reports.* -
  • Out of 76 patients diagnosed with acute AIH between January 2019 and February 2023, only 6 women (aged 40+) developed symptoms within 42 days post-vaccination, suggesting a very low incidence.* -
  • Both observed-over-expected and self-controlled case series analyses showed no statistically significant increase in AIH cases post-vaccination, indicating that COVID-19 mRNA vaccines don't appear to raise the risk for this condition, though more extensive studies are needed.*
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