Publications by authors named "D C Currow"

Background: Low-dose morphine may be prescribed to reduce chronic breathlessness in chronic obstructive pulmonary disease (COPD). Recent subjective findings suggest morphine may influence breathlessness through sleep-related mechanisms. However, concerns exist regarding opioid safety in COPD.

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Article Synopsis
  • This study examined how well different measures assess improvements in chronic breathlessness during clinical practice and research, particularly focusing on patients with chronic obstructive pulmonary disease.
  • A total of 284 elderly men with severe chronic breathlessness participated, and findings indicated that certain measures were more effective in tracking improvements, while others provided similar responses.
  • The results emphasized that assessing the worst breathlessness experienced may be crucial, and highlighted that recall timeframe and thresholds for meaningful improvement significantly impact the evaluation of breathlessness.
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Purpose: The EQ-5D has been used to assess health related quality of life (HRQoL) in respiratory conditions. However, the core descriptive system may not be sensitive to all the HRQoL impacts of these conditions. To increase the sensitivity of the descriptive system, two respiratory specific bolt-ons, have been developed.

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