Publications by authors named "D C Brune"
Background: Assessing health-related quality of life (HRQoL) is a widely employed method in orthopedics to evaluate patient well-being and measure the effectiveness of surgical interventions. Understanding the relationship between specific baseline factors and preoperative HRQoL can help clinicians identify patients at risk for low quality of life and thus, develop preventive strategies that adequately address individual patient needs. The objective was to assess associations between baseline factors and preoperative HRQoL in patients undergoing arthroscopic rotator cuff repair (ARCR).
View Article and Find Full Text PDFBackground: Reverse total shoulder arthroplasty (RTSA) is commonly performed to reduce pain and restore shoulder function in patients with severe shoulder conditions. While most patients experience significant pain relief and functional improvement following surgery, a subset of patients continue to report persistent pain even two years postoperatively. The aim of this study was to identify both modifiable and non-modifiable preoperative factors that contribute to the risk of persistent postsurgical pain after RTSA.
View Article and Find Full Text PDFArticle Synopsis
- Rotator cuff repair surgery is known for its high pain levels, but postoperative pain management isn't frequently studied; the research aimed to understand how pain outcomes relate to recovery after arthroscopic surgery and how pain coping mechanisms influence this relationship.
- The study included 83 patients who had the surgery, measuring pain with the Brief Pain Inventory and shoulder function with the Oxford Shoulder Score, while also exploring various coping strategies through the Coping Strategies Questionnaire.
- Results showed that 24% of patients experienced chronic pain six months post-surgery, and better functional recovery was linked to positive coping strategies, notably self-statements, highlighting the importance of cognitive approaches in enhancing patient outcomes.
Article Synopsis
- * A total of 1987 patients were assessed using various pain and function scales, alongside evaluating demographic and surgical characteristics.
- * Key predictors for CPSP included preoperative negative emotions, existing pain, and shoulder function, emphasizing the need for better pre-surgery evaluations of psychological and social influences on pain outcomes.
Article Synopsis
- A phase 1 trial tested the safety and immune response of an mRNA-based vaccine, mRNA-1647, for cytomegalovirus (CMV) in both seronegative and seropositive adults.
- 154 participants were involved, with most reporting mild to moderate adverse reactions and no serious side effects noted.
- The results indicated that mRNA-1647 was safe and effective in stimulating both antibody and cell-mediated immune responses in participants.