Publications by authors named "D C Bean"

Article Synopsis
  • The study evaluated the effectiveness of interdisciplinary pain management programs (IPMPs) for complex regional pain syndrome (CRPS) compared to low back pain (LBP) and chronic widespread pain (CWP).
  • Researchers found that recovery trajectories for pain interference and pain intensity were similar across CRPS, LBP, and CWP patients, indicating equivalent benefits from IPMPs.
  • Machine learning models were successfully used to predict recovery outcomes based on initial characteristics, classifying 69% for pain interference and 88% for pain intensity recovery trajectories.
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Polymyxin antibiotics B and colistin are considered drugs of last resort for the treatment of multi-drug and carbapenem-resistant Gram-negative bacteria. With the emergence and dissemination of multi-drug resistance, monitoring the use and resistance to polymyxins imparted by mobilised colistin resistance genes () is becoming increasingly important. The genus is widely disseminated throughout the environment and serves as a reservoir of -3, posing a significant risk for the spread of resistance to polymyxins.

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Many endosymbionts of insects have been shown to manipulate and alter their hosts' reproduction with implications for agriculture, disease transmission, and ecological systems. Less studied are the microbiota of classical biological control agents and the implications of inadvertent endosymbionts in laboratory colonies for field establishment and effects on target pests or nontarget organisms. While native-range field populations of agents may have a low incidence of vertically transmitted endosymbionts, quarantine and laboratory rearing of inbred populations may increase this low prevalence to fixation in relatively few generations.

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Recent documented infection with an endemic coronavirus (eCoV) associates with less severe coronavirus disease 2019 (COVID-19), yet the immune mechanism behind this protection has not been fully explored. We measured both antibody and T cell responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in SARS-CoV-2 naïve individuals classified into two groups, either with or without presumed recent eCoV infections. There was no difference in neutralizing antibodies and T cell responses against SARS-CoV-2 antigens between the two groups.

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Aims: Antibiotic resistance is a global health crisis. Roughly two-thirds of all antibiotics used are in production animals, which have the potential to impact the development of antibiotic resistance in bacterial pathogens of humans. There is little visibility on the extent of antibiotic resistance in the Australian food chain.

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