Innovative Emulsifiers in Cosmetic Products: A Patent Review (2013-2023).

The cosmetics industry, characterized by innovation and dynamism, is constantly undergoing research, often guided by market trends. Although it covers various sectors, emulsifiers have had a notable impact on its development. Numerous products depend on these components, and continuous research has led to the creation of ever-better products.

Correlations Between Facet Tropism, Joint Mobility and Degree of Displacement in Patients with Low Grade Spondylolisthesis.

Aim: To compare lumbar X-ray and magnetic resonance imaging (MRI) findings, and to identify the factors associated with joint instability in cases with lumbar spondylolisthesis.

Material And Methods: We performed a retrospective and observational study of patients with a confirmed diagnosis of lumbar or lumbosacral low-grade spondylolisthesis at a single level. Preoperative X-ray and MRI examinations were evaluated.

Advanced trends in detecting boldenone, its metabolites, and precursors in biological matrices: an integrative review of chromatographic methods.

Boldenone (BOL) has been frequently detected in doping and food safety over the past few decades. Researchers have studied BOL metabolism across various species, reporting significant differences even within the same species due to variations in experimental designs and analytical methods. Additionally, detection methods face challenges such as matrix interferences and the presence of endogenous structural analogs at low concentrations.

Effect of poly(ε-caprolactone) microspheres on population pharmacokinetic/pharmacodynamic model of a simple coumarin.

This study aims to evaluated the impact of poly(ε-caprolactone) (PCL) microspheres on the pharmacokinetics and pharmacodynamics (PopPK/PD) of 6-methylcoumarin (6MC). For this, PCL microspheres loaded with 6MC were prepared using the emulsification-evaporation method. Particle size, zeta potential, drug loading, and entrapment efficiency were characterised by dynamic light scattering and UV spectrophotometry.

Rutin and Extract: Population Pharmacokinetics in New Zealand Rabbits.

An extract of calyces from with hypoglycemic activity is being considered as a potential herbal medicine. Preclinical pharmacokinetics (PK) studies of the extract in rats, focusing on plasma concentrations of its main compound, rutin, and its metabolites, revealed PK interactions in the extract matrix that improved the absorption of rutin metabolites compared to the pure compound, among other PK effects. This research aimed to study the PK of rutin alone and in the extract and assess potential PK interactions in the extract matrix on the flavonoid and its metabolites in rabbits, a nonrodent species; Animals received pure rutin or extract orally and intravenously.