Publications by authors named "D C Agarwal"
Pulmonology
December 2025
Article Synopsis
- Spirometry is a test used to evaluate lung function by comparing it to normal levels in healthy non-smokers, focusing on metrics like forced vital capacity (FVC) and the FEV/FVC ratio.
- The study analyzed data from over 14,000 participants aged 40 and older across 41 sites, revealing regional differences in FVC tied to factors like age and height, categorized into four regions: Europe/richer countries, Near East, Africa, and Far East.
- Findings showed significant regional variations in FVC values between men and women, particularly in Europe compared to the Far East, but minimal differences in the FEV/FVC ratio across regions.
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Crit Rev Immunol
November 2024
Article Synopsis
- There is a growing number of cancer cases prompting research into its causes, which has led to new targeted immunotherapy strategies that aim to reduce the negative effects of traditional chemotherapy and radiotherapy.
- Various targeted immunotherapies have been tested for their effectiveness, such as vaccines that use specific tumor-related antigens, checkpoint blockade therapies involving monoclonal antibodies, and adoptive cell transfer methods like CAR-T cell therapies.
- The text reviews recent progress in these targeted immunotherapeutic strategies while also discussing their limitations in treating cancer.
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J Assoc Physicians India
November 2024
Article Synopsis
- India faces a growing epidemic of cardiovascular diseases, particularly coronary artery disease, due to rapid urbanization and globalization, with over 7 million deaths annually from CAD.
- Key challenges in low- and middle-income countries include a lack of awareness about risk factors, healthcare access, and affordability of treatment.
- Effective management of angina pectoris involves collaboration among patients and healthcare providers and utilizes both first-line (like CCBs and β-blockers) and second-line antianginal medications to improve patient outcomes.
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BMC Infect Dis
November 2024
Article Synopsis
- Tuberculosis is common in India, while Histoplasmosis is less reported; co-infection is rare but challenging to diagnose due to symptom overlap.
- A 62-year-old man was diagnosed with both conditions, initially treated with appropriate medications, but experienced complications due to drug interactions.
- Follow-up treatment adjustments led to significant improvement, highlighting the need for careful monitoring and awareness of potential drug interactions in similar cases.
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