Maternal serum apelin-13 levels in early- and late-onset preeclampsia.

Objective: To assess whether alterations in maternal serum apelin-13 levels differ between early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE).

Materials And Methods: A prospective case-control study included 90 preeclamptic cases and 90 normotensive healthy pregnant women as controls. Preeclampsia cases were subclassified as EO-PE and LO-PE.

A Paradigm Shift in Renal Cell Carcinoma: Recognizing Hypoglycaemia as a Significant Paraneoplastic Syndrome.

Recurrent hypoglycaemia is a rare paraneoplastic syndrome associated with several cancers, including renal cell carcinoma (RCC). Here we present a curious case of a patient with type 2 diabetes mellitus (T2DM) who had numerous hospitalisations due to recurrent hypoglycaemia. A well-defined lesion at the lower pole of the right kidney and bilateral pyelonephritis were found during imaging investigations.

Design and analysis of UPQC in a microgrid using model reference adaptive control ensemble with back-stepping controller.

In recent years, the power sector has shifted to decentralized power generation, exemplified by microgrids that combine renewable and traditional power sources. With the introduction of renewable energy resources and distributed generators, novel strategies are required to improve reliability and quality of power (PQ). In our proposed system, a model consisting of photovoltaics, wind energy, and fuel cells has been designed to share a network, bolstered by the integration of UPQC to rectify PQ issues.

Final Analysis of a Noninterventional Study on Cabozantinib in Patients With Advanced Renal Cell Carcinoma After Prior Checkpoint Inhibitor Therapy of the German Interdisciplinary Working Group on Renal Tumors (IAG-N).

Background: Efficacy of treatment after failure of check point inhibitors (ICI) therapy remains ill-defined in metastatic renal cell carcinoma (mRCC).

Objective: To evaluate the safety and effectiveness of cabozantinib after failure of ICI-based therapies.

Design, Setting And Participants: Patients with mRCC who concluded cabozantinib treatment directly after an ICI-based therapy were eligible.

Clinico-demographic and biochemical correlation of inflammatory gene expression in pediatric nephrotic syndrome.

Background: Nephrotic syndrome (NS) is a common kidney disease in children. While Steroid-Sensitive Nephrotic Syndrome (SSNS) is frequently observed, Steroid-Resistant Nephrotic Syndrome (SRNS) has a poor prognosis and often leads to chronic kidney disease. The pathogenesis of SRNS is complex, with immunological modulation of T helper subtypes 1 and 2 cytokines increasing susceptibility to the disease.