No difference in outcomes after remplissage or open Bankart repair plus inferior capsular shift in collision and contact athletes with subcritical glenoid bone loss ≤ 10 % and off-track Hill Sachs lesion.

Purpose: To compare functional outcomes, recurrence rate, range of motion (ROM) and return to sport between arthroscopic Bankart repair with remplissage (BR) and open Bankart repair with inferior capsular shift (OBICS) in contact and collision athletes with recurrent anterior shoulder instability.

Methods: A prospective comparative cohort study of 90 patients separated into two study groups (OBICS and BR) of 45 collision and contact athletes each was conducted. All athletes had subcritical glenoid bone loss (SGBL) ≤ 10% and off-track Hill Sach lesions (HSLs).

Phytochemical screening and biological properties of Quintral flower polyphenolic fractions.

flower is used in traditional medicine for its antioxidant and antibacterial properties, which are attributed to phenolic compounds. These compounds present different grades of associations with the plant matrix (free, esterified, and insoluble). This study aimed to determine which fraction contributes the most to total phenolic and flavonoid contents and bioactive properties.

Novel apocynin regulates TRPV1 activity in the trigeminal system and controls pain in a temporomandibular joint neurogenic model.

Objective: Herein, we investigate the potential analgesic effect of a newly synthesized chalcone-derived apocynin in a neurogenic pain model.

Methods: Molecular docking was used to foretell the apocynin binding features and dynamics with the TRPV1 channel, and the activity was tested in vitro, using transfected HEK 293T cells with the rat TRPV1 receptor. The analgesic effect of apocynin was investigated using a capsaicin-induced pain model.

Intrinsic structural disorder on proteins is involved in the interactome evolution.

New mathematical tools help understand cell functions, adaptability, and evolvability to discover hidden variables to predict phenotypes that could be tested in the future in wet labs. Different models have been successfully used to discover the properties of the protein-protein interaction networks or interactomes. I found that in the hyperbolic Popularity-Similarity model, cellular proteins with the highest contents of structural intrinsic disorder cluster together in many different eukaryotic interactomes and this is not the case for the prokaryotic E.