Publications by authors named "D Burke"
Article Synopsis
- Type B aortic dissection with serious complications, like a large entry tear and circumferential dissection, poses a higher risk of progression and rupture without surgery.
- Traditional treatment involves complicated procedures to prevent stroke when placing a stent, but new endovascular graft technology has improved treatment options.
- A case study of a 53-year-old man with a severe type B dissection demonstrates a two-step treatment approach using carotid bypass followed by endovascular repair with a GORE TAG device.
Article Synopsis
- * While tyrosine kinase inhibitors (TKIs) have improved survival, resistance and disease progression are common, highlighting the need for new treatment options.
- * Research shows that an anti-EGFR aptamer (EGFRapt) can reduce tumor growth in LUAD cells with specific mutations, offering a promising alternative therapeutic strategy that operates through different mechanisms than current treatments.
Highly pathogenic avian influenza A(H5) viruses globally impact wild and domestic birds, and mammals, including humans, underscoring their pandemic potential. The antigenic evolution of the A(H5) hemagglutinin (HA) poses challenges for pandemic preparedness and vaccine design. Here, the global antigenic evolution of the A(H5) HA was captured in a high-resolution antigenic map.
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- Sarcopenia, a muscle-wasting syndrome, is prevalent among older patients with advanced colorectal cancer and is exacerbated by chemotherapy, leading to increased toxicity, reduced quality of life, and lower survival rates.
- This review systematically evaluated existing studies on the effects of physical activity and nutritional interventions on muscle mass specifically in patients with advanced colorectal cancer, identifying gaps in research focused on this demographic.
- Out of twelve studies reviewed, most reported heterogenous interventions, with a few demonstrating benefits from protein supplementation, aerobic exercise, and resistance training, though challenges included low recruitment rates and moderate to high risk of bias.
Background: Apolipoprotein L1 gene () variants are risk factors for chronic kidney disease (CKD) among Black Americans. Data are sparse on the genetic epidemiology of CKD and the clinical association of variants with CKD in West Africans, a major group in the Black population.
Methods: We conducted a case-control study involving participants from Ghana and Nigeria who had CKD stages 2 through 5, biopsy-proven glomerular disease, or no kidney disease.