Publications by authors named "D Bumbacea"

Article Synopsis
  • The study investigates the impact of exacerbations of Chronic Obstructive Pulmonary Disease (ECOPD) on global mortality and hospital readmission rates after hospitalization.
  • The analysis included data from 65,945 COPD patients, revealing a 6.2% in-hospital mortality rate and significant post-discharge mortality and readmission rates at various intervals.
  • Researchers emphasize the need for standardized management of ECOPD and suggest that policymakers prioritize funding for effective therapies to reduce the incidence of recurrent hospitalizations.
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Article Synopsis
  • * Researchers studied 1,909 sarcoidosis patients across Europe, genotyping them for specific genetic markers to see if there were connections between these markers and the disease's various phenotypes.
  • * The study found no broad genetic associations after adjusting for multiple tests, but did identify specific genetic links to acute onset in certain regions (like Serbia and Poland), implying that local environmental factors might influence these genetic effects.
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Esophageal pressure (Pes) measurements could optimise ventilator parameters in acute respiratory failure (ARF) patients requiring noninvasive ventilation (NIV). Consequently, the objectives of our study were to evaluate the safety and accuracy of applying a Pes measuring protocol in ARF patients with AECOPD under NIV in our respiratory intermediate care unit (RICU). An observational cohort study was undertaken.

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Childhood interstitial lung disease (chILD) includes a heterogeneous spectrum of rare respiratory disorders in children associated with substantial morbi-mortality. Interstitial tissue, and other pulmonary structures, epithelium, blood vessels, or pleura are involved, resulting in a restrictive lung disfunction. Respiratory symptoms set in progressively and are often subtle, making thorough clinical history and physical examination fundamental.

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Objective: The critical role played by the nutritional status in the complications, duration of hospitalization and mortality in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) has emerged from several research studies in diverse populations. Obesity has been associated with an increased risk of serious complications, as the adipose tissue appears to have significant effects on the immune response. The aim of this narrative review was to investigate the relationship between COVID-19 and obesity.

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