Publications by authors named "D Bujarbaruah"
Article Synopsis
- Fulminant hepatic failure (FHF) can be a deadly result of hepatitis A virus (HAV) infection, and this study investigates the role of the RANTES-CCR5 signaling pathway in its development.
- The research utilized computational methods, lab experiments, and patient data to assess immune responses, showing that RANTES levels were higher in FHF cases, while monocyte and T-cell activation was reduced.
- Ultimately, the findings suggest that targeting the RANTES-CCR5 pathway could be a helpful strategy in managing patients at high risk for severe HAV outcomes.
RANTES levels as a determinant of falciparum malaria severity or recovery.
Parasite Immunol
September 2017
The study explored the role of differential RANTES concentrations, its receptor CCR5 expression and resulting immunomodulation in the pathogenesis and/or recovery from falciparum malaria. The study population included cases of uncomplicated malaria (UC-M, N=128, enrolled on follow-up basis), severe malaria (SM, N=25), and healthy controls (N=112). Serum RANTES and TNF-α levels were evaluated by ELISA.
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