Publications by authors named "D Bouscary"
Inflammation in Waldenström Macroglobulinemia (iWM) predicts outcomes after immuno-chemotherapy and BTK inhibitors, but its origin is unknown. Here, we unravel increased clonal hematopoiesis in iWM patients (61% versus 23% in non-inflammatory WM), suggesting a contribution of environmental cells to iWM.
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- Primary testicular lymphoma (PTL) is a rare form of diffuse large B-cell lymphoma (DLBCL), making up 1%-2% of DLBCL cases and is linked to poor outcomes due to high rates of central nervous system relapse.
- In a study of 15 patients (5 with PTL and 10 with DLBCL involving the testes), treatment with high-dose methotrexate and R-CHOP showed a 73% complete response (CR) rate overall, with 100% CR in PTL patients and only 55% in DLBCL-T patients.
- The molecular similarities between PTL and primary CNS lymphoma (PCNSL) indicate they may have common origins, highlighting
Article Synopsis
- * Researchers excluded pregnancies that ended in termination or miscarriage and those with prior blood cancer histories, focusing on the survival rates and maternal health during these malignancies compared to healthy pregnancies.
- * The study found that of nearly 10 million pregnancies analyzed, 1,366 were associated with haematological cancers, providing new insights into their incidence and effects on maternal morbidity and mortality.