Purpose: We review the current knowledge about fibromyalgia, adding to the clinical aspects, the nosology, epidemiology and pathogenesis. The therapeutic and social management of these suffering patients are discussed.
Key Points: The limitations of the American College of Rheumatology classification criteria used as diagnostic criteria are discussed.
Non steroidal antiinflammatory drugs (NSAID) used to be the only drugs active in ankylosing spondylarthritis (AS). However, they are inadequate or ill-tolerated in many patients, and have no proven impact on disease-related structural changes. Clinical trials have recently shown the impressive efficacy of two anti-TNFalpha agents (infliximab and etanercept) in patients with NSAID-resistant SA.
View Article and Find Full Text PDFIntroduction: Osteoporosis is characterized by a decrease in bone mass and a change in bone microarchitecture. This causes skeletal fragility and may result in fractures. Fractures of the femur neck (FM) are frequent and have major consequences in terms of morbidity and mortality in elderly subjects.
View Article and Find Full Text PDFRadiculopathy resulting from ossification of the ligamentum flavum (OLF) is extremely rare and concerns only intercostal neuralgias. We describe a 37-year-old Caucasian woman with a lumbar radiculopathy revealing an OLF. Her symptoms were completely and definitively relieved by surgery.
View Article and Find Full Text PDFObjective: To describe characteristics of cases of sarcomatous degeneration in Paget's disease (SDP) recorded over 10 years in 2 French university hospitals, with particular emphasis on the pattern of this entity on magnetic resonance imaging (MRI).
Methods: Fourteen cases are described. Epidemiological, clinical, radiological, histological, and MRI features (in 3 cases) are compared to others in the literature.