Publications by authors named "D Blockmans"
Article Synopsis
- This study aimed to assess how giant cell arteritis (GCA) presents and its outcomes for patients with and without large vessel vasculitis (LVV) while considering the severity of LVV.
- Out of 238 GCA patients analyzed, 71% had LVV, with younger ages and a higher proportion of females observed among LVV patients; those without polymyalgia rheumatica (PMR) symptoms had a higher risk of relapse and a lower chance of stopping glucocorticoids compared to those with PMR symptoms.
- The findings suggest that LVV is a relapse risk factor in GCA patients without PMR symptoms, with a greater relapse risk linked to a
Objectives: To evaluate differences in presentation and outcome of giant cell arteritis (GCA) patients with and without polymyalgia rheumatica (PMR) symptoms.
Methods: Consecutive patients diagnosed with GCA between 2000 and 2020 and followed for ≥12 months at the University Hospitals Leuven (Belgium), were included retrospectively.
Results: We included 398 GCA patients, of which 181 (45%) with PMR symptoms.
Background: Giant cell arteritis is an age-related vasculitis that mainly affects the aorta and its branches in individuals aged 50 years and older. Current options for diagnosis and treatment are scarce, highlighting the need to better understand its underlying pathogenesis. Genome-wide association studies (GWAS) have emerged as a powerful tool for unravelling the pathogenic mechanisms involved in complex diseases.
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