Standardized Multimodal Pain Protocol Minimizes Inpatient Opioid Administration in Pediatric Orthopedic Surgery Population.

Background: Optimal management of post-operative pain is a critical component of orthopedic surgical care. There is a heightened awareness of narcotic prescribing habits given the current "opioid epidemic." The lack of standardized protocols has led to increased errors, delayed access to prescribed medications, and excessive narcotic prescribing.

Racial discrimination and adverse childhood experiences predicting depressive symptoms and developmental assets: Testing cultural socialization and preparation for bias as moderators among Black adolescents and caregivers.

The current study examined whether adverse childhood experiences and racial discrimination predicted adolescents' internal developmental assets, external developmental assets, and depressive symptoms. We also tested whether these relations were buffered by aspects of caregivers' reports of ethnic-racial socialization efforts (i.e.

Oral Pathobiont-Derived Outer Membrane Vesicles in the Oral-Gut Axis.

Oral pathobionts are essential in instigating local inflammation within the oral cavity and contribute to the pathogenesis of diseases in the gastrointestinal tract and other distant organs. Among the Gram-negative pathobionts, and emerge as critical drivers of periodontitis, exerting their influence not only locally but also as inducers of gut dysbiosis, intestinal disturbances, and systemic ailments. This dual impact is facilitated by their ectopic colonization of the intestinal mucosa and the subsequent mediation of distal systemic effects by releasing outer membrane vesicles (OMVs) into circulation.

Design and construction of a servomechanism using a memory alloy linear actuator.

This work shows the design and construction of a servomechanism of a rotator-type joint based on NiTi Shape Memory Alloys (SMA) with an angular position measurement based on a potentiometer sensor and digital electronic position control. The expected application of this prototype is for the use of small charges that emulate the movement of the human being, being bio-inspired and activated by artificial muscles, their potential applications they will be in medical and humanoid robotics. Computer Aided Design (CAD) allows evaluating and validating the most convenient parameters for construction of servomechanism, experimental results validate allowed us to obtain the values of the range of motion and a maximum torque of 1.