3D pull-out finite element simulation of the pedicle screw-trabecular bone interface at strain rates.

Biomedical experimental studies such as pull-out (PO), screw loosening experience variability mechanical properties of fresh bone, legal procedures of cadaver bone samples and time-consuming problems. Finite Element Method (FEM) could overcome experimental problems in biomechanics. However, material modelling of bone is quite difficult, which has viscoelastic and viscoplastic properties.

Experimental investigation of pull-out performance of pedicle screws at different polyurethane (PU) foam densities.

Pedicle bone screws are one of the most critical materials used in spinal orthopaedic operations. Screw loosening and pull-out (PO) are basic complications encountered during or after surgery. Pull-out Strength (POS) of the bone is one of the significant parameters to understand the mechanical behaviour of a screw fixed to poor quality or osteoporotic bone.

The detection of curcumins' antitumoral effects via argyrophilic nucleolar organizing region-associated protein synthesis in mice with ehrlich's ascitic carcinoma.

Background: Curcumin is a polyphenol compound that has antioxidant, anticancer, anti-inflammatory, anti-hyperlipidemic and antimicrobial effects. Nucleolar-organizing regions are the sites of the gene on chromosomes. The present study was aimed to show the antitumoral effect of curcumin via AgNOR protein synthesis in Ehrlich's ascitic carcinoma (EAC) bearing mice.

May argyrophilic nucleolar organizing region-associated protein synthesis be used for selecting the most reliable dose of drugs such as rhamnetin in cancer treatments?

Background: Rhamnetin is a flavonoid that has antioxidant, anti-inflammatory and anti-cancer effects. Nucleolar-organizing regions are the ribosomal genes region. We aimed to identify whether rhamnetin has an effect on cell proliferation and whether AgNOR proteins may be used for the detection of therapeutic benefits of the drugs and new metabolites, which have the potential of being used for cancer treatments.