Oxford-AstraZeneca COVID-19 vaccine: need of a reasoned and effective vaccine campaign.

Objectives: A strong COVID-19 vaccine campaign is needed to reach the herd immunity and reduce this pandemic infection.

Study Design: In the Foch Hospital, France, in February 2021, 451 healthcare workers were vaccinated by a first dose of AstraZeneca vaccine.

Methods: Adverse effects were reported to our pharmaco-vigilance circuit, by an online and anonymous questionnaire following the first weeks of the vaccinal campaign to healthcare workers.

CDK4/6 inhibitors in P16/HPV16-negative squamous cell carcinoma of the head and neck.

Purpose: Addition of CDK4/6 inhibitors to a variety of established treatments in squamous cell carcinoma of the head and neck (SCCHN) has the potential to improve responses to other therapies and may help overcome treatment resistance. The SCCHN is a heterogeneous group of cancers of the oral cavity, the pharynx and the larynx with poor prognosis despite the aggressive multimodal therapies. In the past decade, significant advances were made in understanding of the molecular and genetic abnormalities leading to oncogenesis in SCCHN.

Multiple scattering efficiency and optical extinction.

In this investigation, scattering of laser light by polystyrene spheres has been examined. Our results demonstrate that certain multiple scattering data can be explained in terms of single scattering Mie theory. Multiple scattering can be interpreted as a succession of independent, single scattering events.