Publications by authors named "D Biacchi"
Management of peritoneal surface malignancies is currently entrusted to a multimodality approach. Computed tomography (CT) scan remains the first imaging method despite the limitations in identifying small implants in critical regions. Magnetic resonance imaging is usually recommended for its performance in small implants, mesentery, and small bowel assessment.
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- The PRECINCT study is a multicenter analysis of surgical documentation and disease incidence in patients with peritoneal tumors, focusing on the surgical peritoneal cancer index (sPCI) and its variations across centers.
- Among 707 enrolled patients from September 2020 to December 2021, the study found that different morphological terminologies were used to describe peritoneal lesions, with the most common being "normal peritoneum," "tumor nodules," and "confluent disease."
- The research revealed that the incidence of pathologically confirmed disease was higher in cases with more severe lesion scores and suggested that using frozen section analysis could be beneficial, indicating the need for larger studies correlating imaging and pathology.
Background: There is little evidence on KRAS mutational profiles in colorectal cancer (CRC) peritoneal metastases (PM). This study aims to determine the prevalence of specific KRAS mutations and their prognostic value in a homogeneous cohort of patients with isolated CRC PM treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
Materials And Methods: Data were collected from 13 Italian centers, gathered in a collaborative group of the Italian Society of Surgical Oncology.
Introduction: The selection of patients undergoing cytoreductive- surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is crucial. BIOSCOPE and COMPASS are prognostic scores designed to stratify survival into four classes according to clinical and pathological features. The purpose of this study is to analyze the prognostic role of these scores using a large cohort of patients as an external reference.
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- Diabetes is a serious health issue that can cause problems like foot ulcers, which might lead to needing to have a toe or foot amputated.
- * In a study, 12 people with foot ulcers were treated with a special therapy called platelet-rich plasma (PRP) to help their wounds heal better.
- * After 6 months, 8 patients completely healed, and 4 showed big improvements, making PRP seem like a helpful treatment for these tough wounds.