Publications by authors named "D Benditt"

Aim: In light of many recent advances in the field of vasovagal syncope, a selective review has been undertaken of these developments.

Methods: Recent publications on the following topics were reviewed; understanding of vasovagal syncope pathophysiology, tilt-testing methodology and interpretation, drug, ablation and pacemaker therapy.

Results And Conclusions: The vasovagal syncope field is very active in researching its pathophysiology, using it to gain better understanding of the process and applying this knowledge to therapy.

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Article Synopsis
  • People with epilepsy face risks of premature death, particularly through sudden unexpected death in epilepsy (SUDEP), sudden cardiac death (SCD), and sudden arrhythmic death syndrome (SADS), which share overlapping causes and mechanisms.
  • Sudden death classification relies on autopsy findings and clinician expertise, with definitions for SUDEP, SCD, and SADS often leading to diagnostic confusion; most SUDEP cases do not involve seizure-induced arrhythmias.
  • Effective risk assessment for sudden death in epilepsy requires a collaborative approach, including thorough clinical evaluations, toxicological tests, genetic analysis, and post-mortem examination, with future research aimed at refining the understanding and management of these conditions.
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Syncope is a symptom in which transient loss of consciousness occurs as a consequence of a self-limited, spontaneously terminating period of cerebral hypoperfusion. Many circulatory disturbances (e.g.

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Atrial fibrillation (AF) is the most common cardiac arrhythmia and if untreated, significantly increases both the risk of intracardiac thrombus formation and ischemic stroke. In patients with nonvalvular AF (NVAF), the left atrial appendage (LAA) has been estimated to be the source of thrombus development in 91% to 99% of cases. Consequently, oral anticoagulation (OAC) to provide stroke prevention has become the standard of care for most AF patients; however, OACs are associated with a risk of bleeding and their efficacy depends on optimal patient compliance.

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