Publications by authors named "D Bear"

Nutrition therapy is a complex intervention with several underlying considerations that may influence effectiveness. Considerations include the mechanism of action of the intervention and the patient phenotype, including sex, ethnicity, body composition, and the patients' nutritional and inflammatory status. Energy and protein targets are elements of nutrition therapy that may be particularly influenced by individual patient factors.

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Background: Surviving critical illness leads to prolonged physical and functional recovery with both nutritional and physical rehabilitation interventions for prevention and treatment being investigated. Nutritional status and adequacy may influence outcome, but no consensus on which nutritional-related variables should be measured and reported in clinical trials exists.

Objectives: This study aimed to undertake a systematic review investigating the reporting of nutritional screening, nutritional status, and nutritional intake/delivery in randomized controlled trials (RCTs) evaluating nutritional and/or physical rehabilitation on physical and functional recovery during and following critical illness.

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Purpose: Gastrointestinal (GI) dysfunction is common in critically ill patients and associated with poor outcomes. There is a lack of standardised methods for daily monitoring of GI function. COSMOGI aimed to develop a Core Outcome Set (COS) for daily monitoring of GI function to improve consistency and comparability in future studies in critically ill patients.

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Article Synopsis
  • The COVID-19 pandemic affected cannabis cultivation behaviors, with a web survey of 11,479 growers across 18 countries revealing that most practices remained stable, though challenges were noted in purchasing cannabis.
  • While 28.2% of respondents reported increased cannabis use, and 21.4% reported growing more cannabis during the pandemic, those who faced job loss or casual employment were notably more likely to increase their cultivation.
  • The study concluded that the pandemic prompted some to start growing cannabis and highlighted that a lack of access to illegal supply chains motivated home cultivation increases, though it acknowledged limitations in sample representation.
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  • Micronutrient (MN) alterations in critically ill patients can lead to complications, but improving MN status may help as a supportive therapy.
  • This review, done by a specialized group, focuses on individual important MNs, such as vitamins A, B, C, D, E, as well as minerals like iron and zinc, to guide future research.
  • It emphasizes that high-dose single MN treatments are not advised; instead, patients should receive daily basal needs, with adjustments for higher requirements and treatment for deficiencies, and lists ongoing trials and future research priorities.
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