The Role of Formononetin in Osteoblast Function and Mineralization Potential with Deproteinized Bovine Bone Material.

Objectives: Dental bone formation involves various cellular and molecular mechanisms, and phytoestrogens such as formononetin (FORM) are promising because of their estrogenic, anti-inflammatory, and antioxidant effects. This study investigated the effect of FORM on osteoblast proliferation, differentiation, and mineralization in combination with spongiosa granulates (BO) in vitro.

Materials And Methods: Human fetal osteoblast cells (hFOB1.

Criteria for early diagnosis of congenitally missing second premolars based on the calcification grades of other permanent posterior teeth: a retrospective study.

Diagnosing congenitally missing second premolars (SPs) in early childhood is challenging due to variations in their calcification ages. In this study, we investigated the correlation between calcification grades of SPs and other permanent posterior teeth to aid clinicians in the early diagnosis of congenitally missing SPs. This cohort study retrospectively evaluated 6813 images from 9261 panoramic image records of children aged 42-78 months.

Planning and performing simultaneous bariatric surgery and robotic hysterectomy in a super-obese patient with endometrial cancer.

Endometrial cancer (EC) is the most common gynecological malignancy in developed countries, and endometrial intraepithelial neoplasia (EIN) is the defined precancerous lesion. Obesity is considered a risk factor for both EC and EIN. On the other hand, mortality is often attributed to obesity-related conditions in patients with early-stage EC.

The role of neoadjuvant chemotherapy before radical surgery in stage IB2/IIA2 squamous cell cervical cancers.

Background: This study aimed to evaluate the outcomes of patients diagnosed with stage IB2/IIA2 cervical squamous cell carcinoma who underwent neoadjuvant chemotherapy (NACT) prior to radical hysterectomy compared to those who did not receive NACT before surgery.

Materials And Methods: This is a multicenter study including data of 6 gynecological oncology departments. The study is approved from one of the institution's local ethics committee.