Pentafluorophenol-Catalyzed Metal-Free Fischer Indole Synthesis: A Novel Approach to Carbazole Derivatives and Desbromoarborescidine A.

Carbazoles represent significant heterocyclic compounds with a wide range of applications in organic synthesis. Conventional techniques, such as the Fischer indole synthesis, have been extensively utilized for the construction of these structures. In this study, we report the first use of pentafluorophenol (PFP) as a catalyst in a metal-free approach for the synthesis of carbazoles.

Comparison of tooth substance loss and angle deviation in access cavity preparation using guided endodontics and conventional method in calcified canals - An in vitro study.

Aims: This study aimed to evaluate the accuracy of access cavity preparation using guided endodontics (GE) and conventional technique (CT) in calcified canals.

Subjects And Methods: Twenty teeth with calcification up to middle third were collected after scanning through RadioVisioGraphy (RVG). Preoperative cone-beam computed tomography (CBCT) scan was done and samples were randomly divided into two groups of ten samples each on the basis of method of access cavity preparation.

A Rare Case of Intravascular Large B-cell Lymphoma Presenting as Fever of Unknown Origin With Unexplained Proteinuria.

Intravascular large B-cell lymphoma (IVLBCL) is a subtype of extranodal diffuse large B-cell lymphoma, characterized by neoplastic B-cell proliferation within blood vessels. Its nonspecific presentation, often as fever of unknown origin (FUO) and systemic symptoms, makes diagnosis challenging. We report the case of a 66-year-old male patient presenting with persistent fever, weight loss, and respiratory failure.