Publications by authors named "D Balvay"
Article Synopsis
- Preeclampsia is a pregnancy-related condition linked to placental problems, studied in mice using the STOX1A model which simulates symptoms like high blood pressure and protein in urine.
- The study compared placental perfusion in two groups of pregnant mice (TgSTOX13 vs. wild-type) using advanced imaging techniques to measure blood flow and other health indicators.
- Results showed that the TgSTOX13 group had significantly higher blood pressure, protein levels in urine, and lower fetal weights, along with a 30% reduction in placental blood flow, reflecting similar issues seen in human preeclampsia cases.
Background: The long isoform of the Wnk1 (with-no-lysine [K] kinase 1) is a ubiquitous serine/threonine kinase, but its role in vascular smooth muscle cells (VSMCs) pathophysiology remains unknown.
Methods: AngII (angiotensin II) was infused in to induce experimental aortic aneurysm. Mice carrying an allele were cross-bred with mice carrying a floxed allele to specifically investigate the functional role of Wnk1 in VSMCs.
Article Synopsis
- The text serves as a correction to a previously published article identified by the DOI 10.1371/journal.pone.0234165.
- The correction addresses specific errors or inaccuracies in the original publication.
- Such amendments aim to ensure the integrity and accuracy of the research findings presented in the article.
Article Synopsis
- * Research conducted on female rodents showed that a single stress event can lead to lasting heart damage, as indicated by changes in blood biomarkers and various imaging techniques.
- * The study highlights that long-term metabolic disruptions in the heart contribute to permanent damage, challenging the idea of Takotsubo being easily reversible and emphasizing the need for early treatment strategies.