Publications by authors named "D B Saris"

Aims: Distal femoral osteotomies (DFOs) are commonly used for the correction of valgus deformities and lateral compartment osteoarthritis. However, the impact of a DFO on subsequent total knee arthroplasty (TKA) function remains a subject of debate. Therefore, the purpose of this study was to determine the effect of a unilateral DFO on subsequent TKA function in patients with bilateral TKAs, using the contralateral knee as a self-matched control group.

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Article Synopsis
  • Traditional treatment for unstable osteochondritis dissecans lesions in the medial femoral condyle involves open surgery with direct visualization.
  • This study introduces an arthroscopic method for treating these lesions which includes elevation, cleaning, and fixation without a large incision.
  • The new technique preserves surrounding soft tissues and enhances recovery by utilizing specialized instruments for a less invasive approach.
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  • The study aimed to determine if there are racial disparities in the receipt of radiation treatment and outcomes for Medicare patients with cervical cancer who were eligible for primary radiation-chemotherapy.
  • The analysis included 1,038 patients (mostly White and some Black), comparing their treatment rates and survival outcomes, revealing that Black patients were more likely to receive radiation therapy but had similar survival rates as White patients.
  • Ultimately, the findings suggested that while Black Medicare patients received more radiation therapy, both racial groups experienced no significant difference in overall survival or cancer-specific survival rates.
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Article Synopsis
  • - The study investigates "meniscons," cells from the meniscus surrounded by their natural matrix, to determine if they can aid in cartilage repair similarly to chondrons, which are known for their regenerative properties.
  • - Researchers isolated and cultured human meniscons from osteoarthritic meniscus tissue and compared their behavior and characteristics to chondrons over a 28-day period, finding similarities in cell growth and production of key cartilage components.
  • - The findings highlight the potential of meniscons for future therapies in treating meniscus injuries, as they demonstrate comparable biochemical activity to chondrons while being quickly isolated, which could streamline treatment approaches.
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Cartilage injuries can present in a diverse setting of anatomic locations, with varying severity, and can impact athletes of all ages and competition levels. Moreover, the timing of when an injury presents introduces an additional dimension to treatment decision-making. Frequently, the level of competition, in conjunction with career trajectory and short-term and long-term athlete goals, will dictate whether a temporary or definitive treatment strategy is ideal.

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