Advancing Cancer Therapy with Quantum Dots and Other Nanostructures: A Review of Drug Delivery Innovations, Applications, and Challenges.

Nanotechnology, particularly quantum dots (QDs), has ushered in a transformative era in the pharmaceutical and medical industries, offering notable opportunities for nanoscale advancements. These nanoscale particles, known for their exceptional optical properties and quantum confinement, have emerged as indispensable tools in cancer drug delivery and bioimaging. This review delves into various drug conjugation techniques with QDs, including covalent linking, non-covalent conjugation, click chemistry, disulfide linkage, and pH-sensitive linkage.

Nanocellulose-doped superabsorbent polymer for improved absorption properties in sanitary pad applications.

An important disposable hygienic absorbent is the female sanitary napkin wherein superabsorbent polymers (SAP) are incorporated into it to increase the absorption capacity. Nevertheless, it has been discovered that SAPs have negative consequences on the environment and the user's health. The present study explores doping nanocellulose, into an acrylic acid-based SAP matrix to enhance absorption performance, leveraging nanocellulose's high surface area and hydrophilicity.

Comprehensive in-silico characterization and expression pattern of calmodulin genes under various abiotic and biotic stresses in Indian mustard ().

Unlabelled: Calcium (Ca⁺) as a secondary messenger has a multidimensional role, including the growth and development of plants and the adaptive response to stress conditions. Calmodulin (CaM), a calcium-binding protein, uniquely binds with these Ca⁺ ions and transmits Ca⁺ signals. Calmodulin proteins have been well-reported in various plants for playing a role in abiotic and biotic stress signaling; however, a comprehensive analysis of the genes of Indian mustard () has not been studied much.

Non-Newtonian Solute Mixing via Protonic Exchange of a Polyelectrolyte Layer: Unveiling Formation of Electroosmotic Vortices.

Biochemical and medical diagnostics are two main fields in which vortex generation in microfluidic devices has several applications. Therefore, the aim of the present endeavor is to investigate the characteristics of a non-Newtonian vortex under the influence of a pH-sensitive polyelectrolyte layer (PEL)-modulated electroosmotic effect in a microchannel. Additionally, it is considered that the bulk solution pH (pH) and ionic concentration of the solution influence the zeta potential.

Deciphering the molecular interactions between monocyte chemoattractant protein and its potential inhibitor suramin.

Chemokines, in coordination with glycosaminoglycans (GAGs) and G protein-coupled receptors (GPCRs), play a critical role in regulating inflammatory responses. Among these, monocyte chemoattractant protein-1, also known as CCL2 stands out for its role in coordinating with other immune molecules to direct macrophage migration, infiltration, and recruitment to inflamed tissues, highlighting this pathway as a promising target for therapeutic intervention. In the present study, suramin, a polysulfonated napthylurea compound, having structure similarity with heparin, initially developed therapeutic for treating Human African Trypanosomas [HAT] was analyzed for its repressive action against CCL2 arbitrated macrophage migration.