Background: The aim of this study was to evaluate the association between simple, combined lipid biomarkers, and 20-year cumulative incidence of new type 2 diabetes mellitus (T2DM) among adults participating in the ATTICA cohort study (2002-2022).
Methods: The present analysis included data from 2000 individuals free of T2DM at baseline (age 43 ± 13 years; 51% women). Sociodemographic, anthropometric, lifestyle, clinical, and biochemical parameters were collected at baseline and follow-up examinations; combined lipid markers were evaluated.
Background And Aims: Cardiovascular disease (CVD) and its related co-morbidities, i.e., type 2 diabetes mellitus (T2DM), hypertension and hypercholesterolemia, have an enormous burden on population health and healthcare systems.
View Article and Find Full Text PDFObjective: The purpose of this study was to examine sex-related differences in the long-term (20-year) incidence of cardiovascular disease (CVD) and its determinants.
Methods: In 2002, 3,042 apparently healthy Greek adults were recruited, and in 2022, the 20-year follow-up was conducted with 2,169 participants, 1,988 of whom had completed CVD assessments. Sex-specific analyses using nested Cox proportional hazards were performed, as well as classification and regression tree (CRT) analysis modeling.
Objectives: This study investigated the cross-sectional relationships of total choline intake with the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) and its progression to liver fibrosis.
Study Design: The study used data on total choline intake, hepatic steatosis, and liver fibrosis from the cross-sectional 2017-2020 National Health and Nutrition Examination Survey, including 24-h dietary recalls and liver ultrasound elastography (FibroScan®).
Main Outcome Measures: Steatosis was defined as a controlled attenuation parameter score ≥ 285dB/m.