Publications by authors named "D B Nandini"

Calcifications in the soft tissues can be accidental findings during diagnostic procedures. Oral squamous cell carcinoma (OSCC) forms the major percentage of oral malignancies; calcifications are rare findings in OSCC. Calcifications are seen as a result of necrosis, chronic inflammations as well as degenerative changes and imbalances of the local calcium and phosphorous environment.

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Lipoma is the most common mesenchymal tumor seen in the trunk and extremities. It is rarely found in the mouth. Clinically, it resembles other lesions and is not considered in the initial diagnosis.

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Objectives: The purpose of this study was to compare the efficacy of prebreakfast tooth brushing (PrBTB) and postbreakfast tooth brushing (PoBTB) with or without a prebrushing rinse in caries prevention through the estimation of count.

Materials And Methods: Sixty consenting dental students were divided into three age-matched groups of 20 each and instructed to follow prebreakfast, postbreakfast tooth brushing, and prebreakfast rinsing plus PoBTB using the Bass technique. Plaque samples were collected at the start and at the end of every quarter for a total of 6 quarters (18 months) for the evaluation of colony-forming unit (CFU) counts.

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Article Synopsis
  • The study focuses on the oral health of individuals with type 1 and type 2 diabetes, highlighting that diabetes can lead to specific oral problems such as xerostomia (dry mouth) and chronic periodontitis.
  • Conducted at a diabetes care center in Chennai, the research involved comparing 110 diabetic patients with 100 healthy non-diabetic individuals to assess oral health using specific dental indices.
  • Results showed a significant link between diabetes and both xerostomia and periodontal disease, but did not support previous findings regarding other oral issues like traumatic ulcers and lichen planus.
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Context: Areca nut (AN) is a potent cytotoxic and genotoxic agent. Oxidative stress-induced by chewing of AN can cause DNA damage leading to nuclear anomalies such as micronuclei (MN) and also alters antioxidant defense mechanisms, leading to genomic instabilities and the development of oral cancer.

Aims: The aim of this study is to study the correlation between the levels of glutathione reductase (GR) and superoxide dismutase (SOD) in exfoliated buccal mucosal cells and the genotoxicity levels (MN count) in chronic AN chewers.

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