[A possible complication of therapeutic plasmapheresis].

Possibility of citric intoxication as a complication of therapeutic plasmapheresis is being discussed on the basis of two clinical observations. Hemodynamic reactions to sodium citrate administration have been noted during reinfusion of auto red cell mass. It is suggested that the development of collapsoid reaction, accompanied by a significant decrease in the total peripheral resistance at a stable cardiac output and cardiac index, is determined by the transition of the ionized calcium of the blood into calcium citrate, and thus the violation of the processes regulating the excitement and constriction of the muscular cells in the peripheral arteries.

[Treatment of terminal forms of icterohemorrhagic leptospirosis].

Complex therapy, using hemosorption in combination with hemodialysis and hyperbaric oxygenation, was suggested for the treatment of patients with terminal stages of icterohemorrhagic leptospirosis. Such complex therapy decreased the mortality rate of patients with terminal stages of icterohemorrhagic leptospirosis from 76-96% to 18-22% and reduced the in-hospital stay from 60-80 to 35-40 days.

Morphology of blood cells and the surface of charcoal by scanning electron microscopy during haemoperfusion in patients with hepatorenal syndrome.

The surface structure of non-spherical natural and spherical polymeric charcoal as well as the composition of blood cells in peripheral blood was studied in 52 patients with hepatorenal syndrome using the scanning electron microscope. Our data have allowed us to conclude that the optimal varieties of charcoal in respect of haemocompatibility are non-coated polymeric charcoals with spherical granules. Moreover, these varieties are characterised by an increased ability to absorb deformed erythrocytes.

[Effect of hypothermia on metabolism in the liver during its preservation].

Twenty experiments were conducted on dogs. The effect of hypothermia of different degree (from 18 to 20 degrees C and from 4 to 6 degrees C) on the carbohydrate metabolism and the extent of solubilization of hepatic enzymes (lactate dehydrogenase, glutamate dehydrogenase, urokaninase, DNA-ase, glucose-6-phosphatase) in prefusion-free preservation of the liver was studied. The preservation efficacy was assessed during the subsequent two-hour normothermic perfusion.